Type
Sandwich ELISA, Biotin-labelled antibody
Applications
Serum, Plasma
Sample Requirements
50 μl/well
Shipping
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Curve
Calibration Range
50–3200 pg/ml
Limit of Detection
19.2 pg/ml
Intra-assay (Within-Run)
n = 8; CV = 4.0%
Inter-assay (Run-to-Run)
n = 6; CV = 7.2%
Spiking Recovery
94,00%
Dilution Linearity
101,60%
Crossreactivity
- bovine Non-detectable
- cat Non-detectable
- dog Non-detectable
- goat Non-detectable
- hamster Non-detectable
- horse Non-detectable
- monkey Non-detectable
- mouse Non-detectable
- pig Non-detectable
- rabbit Non-detectable
- rat Non-detectable
- sheep Non-detectable
- chicken Not tested
- human Yes
Features
- It is intended for research use only.
- The total assay time is less than 3.5 hours.
- The kit measures sRAGE in serum and plasma (EDTA, citrate, heparin).
- Assay format is 96 wells.
- Standard is recombinant protein based
- Quality Controls are human serum based. No animal sera are used.
- Components of the kit are provided ready to use, concentrated or lyophilized.
Research topic
Diabetology - Other Relevant Products, Neural tissue markers, Pulmonary diseases, Renal disease
Summary
The receptor for advanced glycation end products (RAGE) is a multiligand member of the immunoglobulin superfamily of cell surface molecules. It mediates interactions of advanced glycation end products (AGE), the products of nonenzymatic glycoxidation of proteins/lipids that accumulate in the plasma and tissues of patients with diabetes.
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
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