Blog - June 2020

• 29 \ 06 \ 2020

  The important role of resistin in the pathology of T2DM

  

  Type-2 diabetes mellitus (T2DM) is a major health problem in the world and many studies have been done in this topic. Nowadays we can certainly say, that pathogenesis of T2DM is connected to obesity-associated insulin resistance and dysglycemia. Despite the fact, that individuals of South Asian descent have a higher risk of developing T2DM for a given body mass index (BMI) compared to Caucasians, majority of the published data was obtained by studying western populations. Moreover, in South Asians, different mechanisms could operate in the pathogenesis of these processes. The pressure for new data in this field is even higher because of recent escalation of obesity in this region.

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• 15 \ 06 \ 2020

  Circulating Biomarkers in Critical Illness and Sepsis

  

  Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. Although sepsis is potentially life-threatening, the illness ranges from mild to severe. 

  Severe sepsis causes poor organ function and/or blood flow and can lead to septic shock. If sepsis progresses to septic shock, blood pressure drops dramatically. This may lead to death. Septic shock is a common cause of mortality mainly in critically ill patients. According to the Mayo Clinic, septic shock has close to a 40 percent mortality rate.

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• 01 \ 06 \ 2020

  Adipokines, batokines and miRNA – molecular markers of “diabesity”

  

  Are you wondering what the term “diabesity” stands for? It expresses the strong association  between type 2 diabetes mellitus (T2DM) and obesity. 75–90% of patients with T2DM are overweight or obese, as obesity is one of the main risk factors for T2DM. Moreover, progression of obesity to T2DM can be partly explained by changes in adipose tissue composition and function. 

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