Blog - Jana Izakova

• 15 \ 06 \ 2020

  Circulating Biomarkers in Critical Illness and Sepsis

  

  Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. Although sepsis is potentially life-threatening, the illness ranges from mild to severe. 

  Severe sepsis causes poor organ function and/or blood flow and can lead to septic shock. If sepsis progresses to septic shock, blood pressure drops dramatically. This may lead to death. Septic shock is a common cause of mortality mainly in critically ill patients. According to the Mayo Clinic, septic shock has close to a 40 percent mortality rate.

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• 09 \ 03 \ 2020

  Adiponectin – metabolic messenger!

  

  The capability to communicate the metabolic state of a cell to neighbouring cells and tissues is crucial for maintaining cellular and organismal energy homeostasis. Unsurprisingly, a wide variety of mechanisms exist to sense, distribute and integrate such information, often involving signals or molecules that travel between cells or to distant organs.

  Today, it is known that adipose tissue is an important and dynamic endocrine organ which produces cell signaling proteins collectively referred to as adipokines. Adiponectin is one member of this family.

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• 16 \ 12 \ 2019

  GDF-15 – messenger of bad news?

  

  Nobody can see into the future, but the blood that courses through your veins may hold some important secrets about your future health – or lack thereof.

  The discovering of prognostic or diagnostic biomarkers for both severe and also minor diseases has a long tradition in health sciences. Researchers all over the world search for new biomarkers which can reveal correct diagnosis, disease severity or even risk of death.

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